CONTROL OF MOS BY CHEMICAL AGENTS CONTD..
They are germicidal, cationic detergents. They are bactericidal against Gran positive bacteria & Gram negative bacteria & are also effective against fungi to certain pathogenic protozoa. Virus appear to be more resistant than bacteria. The two popular quats are Zephiran, a brand mane of benzalkonium chloride & Cepacol, a brand name of cetylpyridinium chloride.Eg Cetrimide . Please visit this link;http://en.wikipedia.org/wiki/Disinfectant
They are used as skin disinfectant, preservatives in ophthalmic solution,& cosmetic preparations. They are widely used for control of mos on floors & walls of hospitals & public places. They are also used to sanitize food & beverage utensils in the restaurant & in food processing plants.
Mode of Action:
They denature protein, interfere with glycolysis & membrane damage. They mostly damage the cytoplasmic membrane by altering the permeability. To know more visit the links below;
H). GASEOUS AGENTS: Gases are used to sterilize heat sensitive item such as syringes, sutures, catheters, etc. The major gases used are ethylene oxide(ETO), Beta- propiolactone , formaldehyde.
- Ethylene Oxide: It is both microbiocidal as well as sporicidal. So, ethylene oxide is also called gaseous autoclave. However, it is carcinogenic & highly explosive. So it should be used with Freon gases or carbon dioxide.
- B-propiolactone: It is occasionally used as sterilizing gas, though it is bactericidal, fungicidal, sporicidal, virucidal , it has low penetration capacity. It is carcinogenic & difficult to handle, so it is used to sterilize serum & vaccines. please visit this link : http://highered.mcgraw-hill.com/sites/0072320427/student_view0/chapter11/chapter_capsule.html, http://www.sciencedirect.com/science/article/pii/S0032959203002784