CONTROL OF MOS BY ANTIBIOTICS

3) INHIBITION OF NUCLEIC ACIDS & PROTEIN SYNTHESIS:


  1. Streptomycin:  Streptomycin is an antibiotic(antimycobacterial) drug, the first class of drugs called aminoglycosides . It is derived from actinobacterium Streptomyces griseus. It was first antibiotic remedy for tuberculosis. Streptomycin is a bactericidal antibiotic. 
 MECHANISM OF ACTION:
Streptomycin is a protein synthesis inhibitor.  It binds to small 16S rRNA of 30S subunit of bacteral chromosome, interfering with the binding of formyl -methiontyl t-RNA to 30S subunit . More on http://en.wikipedia.org/wiki/Streptomycin.
To know more please follow this links:
http://www.rxlist.com/streptomycin-drug.htm
http://www.webmd.com/drugs/drug-11249-streptomycin+im.aspx?drugid=11249&drugname=streptomycin+im
http://livertox.nih.gov/Streptomycin.htm
http://www.drugs.com/cdi/streptomycin.html




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