CONTROL OF MOS BY CHEMICAL AGENTS CONTD..

C. HALOGENS:

2) IODINE:  It is slightly larger than chlorine atom & more germicidal & reactive. It is slightly soluble in  water & readily soluble in alcohols & aqueous solution of sodium & potassium iodide. It is used in several forms like;
  •  Tincture of iodine: It consists of 2% iodine & sodium iodide dissolved in ethanol. It is used for the disinfection of water, & as antiseptics for wounds. 
  • Iodophors: It is iodine detergent complex that release iodine over a long period of time & hence added advantage of non-staining tissues or fabrics. The detergent complex portion of complex looses the organism from the surfaces & halogens kills them. Examples: Beta dine which is a povidone-iodine. Povidone is  a surface active iodophor that improves the wetting action  & serves as reservoir of free iodine. It is used for local wound cleaning.  Wescodyne is used in pre-operative skin. 
USES:
  Disinfection in skin, water, air, Sanitization of food & utensils.  

MODE OF ACTION:
   Iodine  kills organisms by oxidizing cells constituents & by iodinating cell's protein. Oxidation leads to inactive metabolic compounds such as protein with sulfhydryl group. Iodinating is halogenation  of Tyrosine amino acid in protein molecules. To know more about mode of action of Iodine please visit this link; 
http://www.ncbi.nlm.nih.gov/pubmed/10409102 
http://cmr.asm.org/content/12/1/147.full
http://curezone.com/blogs/fm.asp?i=1413057
http://www.drugs.com/mmx/iodine-tincture.html 








   

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